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In the placenta, sts deficiency results in failure of cleavage of estriol sulfate and placental estriol deficiency. In the skin, sts is located. Clinical and biochemical data of 16 typical cases of placental sulfatase deficiency have been observed. In vivo loading tests with dha-s allowed us to make. Recessive x-linked ichthyosis (xli; mim #308100), also called steroid sulfatase (sts) deficiency, is an x-linked recessive ichthyosis caused by. Placental sulfatase deficiency has been found in four pregnancies (cases 1 to 4) with inappropriately low levels of urinary estriol excretion (less than 1. A pregnancy with placental sulfatase deficiency was suspected when a 36-year-old patient at 41 weeks of gestation was found to have extremely low urinary. Summary: placental steroid sulfatase deficiency is a genetic disorder only recently reported in the medical literature. The sulfatase deficiency can be detected during pregnancy by a prolongation of the half-life of dehydroepiandrosterone sulfate (dhas) after venous dhas loading. In 1969, france and liggins described the first case of placental sulfatase deficiency: this enzyme defect is characterized by a lack of the placental enzymatic
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